Analytical Data
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基因名
SAT1
- Application
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别名
SAT1;SAT;Diamine acetyltransferase 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P21673
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表达区间
5-171aa
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氨基酸序列
VIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE
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分子量
26.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SAT1 (Spermidine/Spermine N1-acetyltransferase 1) is an important enzyme involved in polyamine metabolism, which plays a crucial role in cellular processes such as growth, differentiation, and apoptosis. As polyamines are vital for cellular function, the study of SAT1 has gained significant interest, particularly in the context of cancer biology and neurodegenerative diseases. Elevated levels of polyamines have been associated with tumor development and progression, making SAT1 a potential biomarker and therapeutic target in oncology. Additionally, SAT1 is implicated in the regulation of inflammation and stress response, linking it to various physiological and pathological conditions. Understanding the structure and function of SAT1, including its reactivity and interactions with other biomolecules, is essential for developing novel therapeutic strategies. Research into SAT1’s recombinant protein has advanced, utilizing techniques such as molecular cloning and protein expression to generate functional variants for study. These recombinant proteins facilitate in-depth investigations into enzymatic activity, regulation, and the effects of post-translational modifications, providing insights into their role in health and disease. Overall, the exploration of SAT1 and its recombinant forms is poised to enhance our understanding of polyamine biology and its implications in various diseases, paving the way for innovative treatments.












