Analytical Data
-
基因名
CUEDC2
- Application
-
别名
CUEDC2；C10orf66;CUE domain-containing Protein 2
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9H467
-
表达区间
1-287aa
-
氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMELERIV SAALLAFVQT HLPEADLSGL DEVIFSYVLG VLEDLGPSGP SEENFDMEAF TEMMEAYVPG FAHIPRGTIG DMMQKLSGQL SDARNKENLQ PQSSGVQGQV PISPEPLQRP EMLKEETRSS AAAAADTQDE ATGAEEELLP GVDVLLEVFP TCSVEQAQWV LAKARGDLEE AVQMLVEGKE EGPAAWEGPN QDLPRRLRGP QKDELKSFIL QKYMMVDSAE DQKIHRPMAP KEAPKKLIRY IDNQVVSTKG ERFKDVRNPE AEEMKATYIN LKPARKYRFH
-
分子量
34 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CUEDC2 (Cterm-Usual E3 Ubiquitin-Dependent Protein-2) is a critical protein involved in various cellular processes, including cell cycle regulation, apoptosis, and the maintenance of genomic stability. Research into CUEDC2 has intensified due to its unique dual functionality; it serves as both an E3 ubiquitin ligase that regulates protein degradation and a participant in key signaling pathways. Dysregulation of CUEDC2 has been implicated in several human diseases, particularly cancer, where its aberrant expression can lead to uncontrolled cell proliferation and tumor progression. Recent studies have focused on characterizing its structure and understanding its interactions with other cellular molecules, which may illuminate the molecular mechanisms underlying its biological roles. The development of recombinant CUEDC2 protein has enabled researchers to perform detailed functional assays and structural analyses, facilitating the exploration of its potential as a therapeutic target. As the scientific community aims to unravel the complexities of CUEDC2's contributions to cellular homeostasis and disease pathology, ongoing investigations promise to reveal valuable insights that could inform the development of innovative strategies for cancer treatment and other disorders associated with its dysfunction.
