Analytical Data
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基因名
PLXNA4
- Application
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别名
FAYV2820; KIAA1550; PLEXA4; Plexin-A4; PlexinA4; PLXA4_HUMAN; plxna4; PLXNA4A; PLXNA4B; PRO34003; UNQ2820/PRO34003
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9HCM2
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表达区间
25-521aa
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分子量
60 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PLXNA4, or Plexin A4, is a member of the plexin family of receptors that play crucial roles in cellular signaling, particularly in the context of developmental biology and neural processes. It is known to interact with semaphorins, a class of guidance cue proteins that are pivotal for axon guidance and neuronal patterning. The dysregulation of PLXNA4 has been implicated in various neurological disorders and cancers, making it a significant target for therapeutic exploration. Recent research has focused on developing recombinant PLXNA4 proteins to study its structure-function relationships and to elucidate its role in signaling pathways. These recombinant proteins can be utilized in biochemical assays to understand their interactions with ligands, as well as their downstream signaling effects. Furthermore, understanding the precise mechanisms of PLXNA4 can provide insights into potential interventions for conditions associated with its dysfunction. Ongoing studies aim to explore the therapeutic potential of modulating PLXNA4 activity and to discover small molecules or antibodies that could influence its signaling dynamics. Thus, research on PLXNA4 recombinant proteins represents a promising avenue for advancing our knowledge of both fundamental biology and the development of novel therapeutic strategies.












