Analytical Data
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基因名
CHN1
- Application
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别名
CHN1；ARHGAP2；CHN；N-chimaerin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P15882
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表达区间
2-459aa
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氨基酸序列
ALTLFDTDE YRPPVWKSYL YQLQQEAPHP RRITCTCEVE NRPKYYGREF HGMISREAAD QLLIVAEGSY LIRESQRQPG TYTLALRFGS QTRNFRLYYD GKHFVGEKRF ESIHDLVTDG LITLYIETKA AEYIAKMTIN PIYEHVGYTT LNREPAYKKH MPVLKETHDE RDSTGQDGVS EKRLTSLVRR ATLKENEQIP KYEKIHNFKV HTFRGPHWCE YCANFMWGLI AQGVKCADCG LNVHKQCSKM VPNDCKPDLK HVKKVYSCDL TTLVKAHTTK RPMVVDMCIR EIESRGLNSE GLYRVSGFSD LIEDVKMAFD RDGEKADISV NMYEDINIIT GALKLYFRDL PIPLITYDAY PKFIESAKIM DPDEQLETLH EALKLLPPAH CETLRYLMAH LKRVTLHEKE NLMNAENLGI VFGPTLMRSP ELDAMAALND IRYQRLVVEL LIKNEDILF
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The CHN1 gene, associated with the encoding of the protein choline transporter-like 1, has garnered significant attention in recent years due to its pivotal role in neuronal function and synaptic transmission. Research has indicated that CHN1 is crucial for choline uptake, which is essential for acetylcholine synthesis, a neurotransmitter that plays a key role in memory, attention, and muscle control. Mutations in the CHN1 gene have been linked to various neurodevelopmental disorders, including intellectual disabilities and autism spectrum disorders, highlighting the importance of understanding its functional mechanisms. Recent studies have focused on the recombinant production of CHN1 protein, which allows researchers to investigate its structure-function relationships and potential interactions with other neuronal proteins. By utilizing advanced recombinant DNA technologies, scientists are better positioned to study the biochemical properties of CHN1, paving the way for the development of targeted therapeutic strategies for conditions associated with CHN1 dysregulation. Given the increasing prevalence of neurodevelopmental disorders, comprehensive research on CHN1 and its protein product is essential for advancing our understanding of these complex conditions and improving intervention approaches.
