Cat: PA1000-619DB

Recombinant Human CIAO1 Protein,His

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Analytical Data

  • Gene name

    CIAO1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    CIAO1;CIA1;WDR39;Probable cytosolic iron-sulfur Protein assembly Protein CIAO1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    O76071

  • Expression Region

    1-339aa

  • AA Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMKDSLVL LGRVPAHPDS RCWFLAWNPA GTLLASCGGD RRIRIWGTEG DSWICKSVLS EGHQRTVRKV AWSPCGNYLA SASFDATTCI WKKNQDDFEC VTTLEGHENE VKSVAWAPSG NLLATCSRDK SVWVWEVDEE DEYECVSVLN SHTQDVKHVV WHPSQELLAS ASYDDTVKLY REEEDDWVCC ATLEGHESTV WSLAFDPSGQ RLASCSDDRT VRIWRQYLPG NEQGVACSGS DPSWKCICTL SGFHSRTIYD IAWCQLTGAL ATACGDDAIR VFQEDPNSDP QQPTFSLTAH LHQAHSQDVN CVAWNPKEPG LLASCSDDGE VAFWKYQRPE GL

  • Molecular Weight

    40 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

CIAO1 (Chloroplast Import Apparatus 1) is a crucial protein involved in the import of nuclear-encoded proteins into chloroplasts, playing a significant role in chloroplast biogenesis and function. The study of CIAO1 has gained importance due to its potential implications in enhancing plant resilience and productivity. Investigating the structure, function, and regulation of CIAO1 can provide insights into the intricacies of chloroplast protein targeting mechanisms. Research indicates that CIAO1 interacts with various components of the translocon at the inner envelope membrane of chloroplasts, facilitating the proper localization of crucial proteins required for photosynthesis and metabolic processes. Additionally, as global challenges such as climate change and food security intensify, understanding the molecular pathways governed by CIAO1 can offer avenues for genetic engineering strategies aimed at improving crop yield and stress tolerance. Enhanced knowledge of CIAO1 and its functions could pave the way for innovative approaches in biotechnology and agriculture, contributing to sustainable food production systems. This growing body of research underscores CIAO1's significance as a focal point in plant biology, highlighting its potential as a target for biotechnological advancements in plant enhancement and adaptation.

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