Analytical Data
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基因名
CD207
- Application
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别名
CD207；CLEC4K；C-type lectin domain family 4 member K
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UJ71
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表达区间
65-328aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSPRFMGTI SDVKTNVQLL KGRVDNISTL DSEIKKNSDG MEAAGVQIQM VNESLGYVRS QFLKLKTSVE KANAQIQILT RSWEEVSTLN AQIPELKSDL EKASALNTKI RALQGSLENM SKLLKRQNDI LQVVSQGWKY FKGNFYYFSL IPKTWYSAEQ FCVSRNSHLT SVTSESEQEF LYKTAGGLIY WIGLTKAGME GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC DKTFLFICKR PYVPSEP
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分子量
32 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CD207, also known as Langerin, is a type II transmembrane protein predominantly expressed on Langerhans cells, which are specialized antigen-presenting cells found in the skin and mucosal tissues. It plays a crucial role in the immune system by facilitating the capture and processing of antigens, particularly those derived from pathogens. The significance of CD207 lies in its ability to form a dendritic network within the epidermis, where it directs the immune response and influences tolerance and immunity. Research on CD207 recombinant protein has garnered attention due to its potential applications in immunotherapy, particularly in developing vaccines and therapeutic strategies against various infections and cancers. By producing CD207 as a recombinant protein, scientists aim to study its structural and functional characteristics, understand its role in antigen presentation, and evaluate its applications in enhancing immune responses. Furthermore, understanding the interactions between CD207 and pathogens could lead to novel approaches for treating diseases characterized by dysfunctional immune responses. Overall, the study of CD207 recombinant protein provides insights into immune regulation and holds promise for advancing therapeutic interventions.
