Analytical Data
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Gene name
CD1e
- Application
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Alternative Names
CD1e；T-cell surface glycoProtein CD1e. membrane-associated
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P15812
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Expression Region
30-305aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSEEQLSFR MLQTSSFANH SWAHSEGSGW LGDLQTHGWD TVLGTIRFLK PWSHGNFSKQ ELKNLQSLFQ LYFHSFIQIV QASAGQFQLE YPFEIQILAG CRMNAPQIFL NMAYQGSDFL SFQGISWEPS PGAGIRAQNI CKVLNRYLDI KEILQSLLGH TCPRFLAGLM EAGESELKRK VKPEAWLSCG PSPGPGRLQL VCHVSGFYPK PVWVMWMRGE QEQRGTQRGD VLPNADETWY LRATLDVAAG EAAGLSCRVK HSSLGGHDLI IHWGGYS
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Molecular Weight
33 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CD1e is a member of the CD1 family of glycoproteins, which play a crucial role in the immune system by presenting lipid and glycolipid antigens to T cells. Unlike classical major histocompatibility complex (MHC) molecules that present peptide antigens, CD1 molecules, including CD1e, are specialized in the presentation of non-peptidic antigens, making them essential for recognizing microbial lipids, self-lipids, and other lipid-based antigens. The study of CD1e is particularly important because it is involved in the activation of specific subsets of T cells, such as invariant natural killer T (iNKT) cells, which have been linked to various immune responses, including anti-tumor immunity and responses to infections. Research on CD1e recombination protein has gained momentum as scientists aim to better understand its structure, function, and the molecular mechanisms underlying its interactions with lipids and T cell receptors. This knowledge could pave the way for developing novel immunotherapies and vaccines, potentially enhancing the ability to manipulate the immune response for therapeutic purposes. Additionally, exploring CD1e's role in autoimmune diseases and infections could provide insights into its contribution to various pathological states, revealing targets for intervention and treatment strategies. Overall, the investigation of CD1e recombined protein serves as a promising frontier in immunology, bridging gaps in our understanding of lipid antigen presentation and its implications for health and disease.
