Cat: PA1000-243DB

Recombinant Human ASCC1 Protein,His

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Analytical Data

  • Gene name

    ASCC1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ASCC1;Activating signal cointegrator 1 complex subunit 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8N9N2-2

  • Expression Region

    1-357aa

  • AA Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMEVLRPQ LIRIDGRNYR KNPVQEQTYQ HEEDEEDFYQ GSMECADEPC DAYEVEQTPQ GFRSTLRAPS LLYKHIVGKR GDTRKKIEME TKTSISIPKP GQDGEIVITG QHRNGVISAR TRIDVLLDTF RRKQPFTHFL AFFLNEVEVQ EGFLRFQEEV LAKCSMDHGV DSSIFQNPKK LHLTIGMLVL LSEEEIQQTC EMLQQCKEEF INDISGGKPL EVEMAGIEYM NDDPGMVDVL YAKVHMKDGS NRLQELVDRV LERFQASGLI VKEWNSVKLH ATVMNTLFRK DPNAEGRYNL YTAEGKYIFK ERESFDGRNI LKLFENFYFG SLKLNSIHIS QRFTVDSFGN YASCGQIDFS

  • Molecular Weight

    44 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ASCC1 (Amplified in Breast Cancer 1) is a protein that has garnered significant attention in cancer research due to its potential role in various malignancies, particularly breast cancer. This gene is often found to be overexpressed in cancer tissues, suggesting a correlation with tumor progression and poor prognosis. ASCC1 is involved in crucial cellular processes, including DNA damage response and repair, transcription regulation, and cell proliferation. Its overexpression may contribute to the survival of cancer cells under stress conditions, such as DNA damage, thereby facilitating tumorigenesis. Recent studies have focused on the biochemical properties of ASCC1 and its interactions with other proteins within cellular signaling pathways, thereby elucidating its functional mechanisms in cancer biology. The recombinant protein form of ASCC1 is being produced to enable more detailed functional assays, structural studies, and potential therapeutic applications. Understanding the intricacies of ASCC1 function can provide novel insights into cancer treatment strategies and may lead to the development of targeted therapies that inhibit its activity, ultimately aiming to improve patient outcomes in cancers where ASCC1 is implicated.

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