Analytical Data
-
Gene name
ARSM2
- Application
-
Alternative Names
ARSM2；2-methyl-6-phytyl-1.4-hydroquinone methyltransferase 1. chloroplastic
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P0C7Q2
-
Expression Region
1-330aa
-
AA Sequence
MKEMVSSSTFRAPGGLGFLGPSKIGLIPLRNRSGVRSRVKYIAPKCAVSSARPASQPRFIQHKKEAFWFYRFLSIVYDHVINPGHWTEDMRDDALEPAELYHHGLKVVDVGGGTGFTTLGIVKHVDNENVTLLDQSPHQLEKARQKVALNGVNIIEGDAEDLPYPTDTFDRYVSAGSIEYWPDPQRGIREAYRVLKLGGVACLIGPVHPTFWLSRFFADMWMLFPKEEEYIEWFQKAGFQDVKIKRIGPKWYRGVRRHGLIMGCSVTGVKRSSGDSPLQLGPKAEDVEKPVNPFTFIFRFVMGTICASYYVLVPIYMWMKDQIVPKDQPI
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ARSM2, or arginyl-tRNA synthetase mitochondrial 2, is a crucial enzyme in mitochondrial protein synthesis, playing a key role in the proper functioning of mitochondrial translation systems. Research on ARSM2 has gained momentum due to its involvement in various cellular processes and its link to mitochondrial diseases, which can lead to severe metabolic disorders. As a member of the aminoacyl-tRNA synthetase family, ARSM2 is responsible for the charging of tRNA with specific amino acids, ensuring accurate protein translation within mitochondria. Mutations in the ARSM2 gene can disrupt mitochondrial function, leading to a range of clinical manifestations, including myopathy, neurological deficits, and developmental issues. Given the increasing recognition of the importance of mitochondrial health in maintaining overall cellular function, studying ARSM2 has significant implications for understanding the molecular mechanisms underlying mitochondrial diseases. Additionally, insights gained from ARSM2 research could pave the way for potential therapeutic interventions aimed at correcting or compensating for the effects of its dysfunction, highlighting the enzyme's importance in both fundamental biology and clinical applications. Recent advancements in molecular biology techniques have facilitated the investigation of ARSM2's structure and function, encouraging further exploration of its role in mitochondrial dynamics and cellular metabolism. This growing body of knowledge not only enhances our understanding of mitochondrial biology but also underscores the necessity for continued research into the implications of ARSM2 in health and disease.
