Analytical Data
-
Gene name
ADGRG6
- Application
-
Alternative Names
(Developmentally regulated G-protein-coupled receptor)(G-protein coupled receptor 126)(Vascular inducible G protein-coupled receptor)
-
Species
Human
-
Source
E. coli
-
Tag
N- His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q86SQ4
-
Expression Region
38-437aa
-
Molecular Weight
46.6 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ADGRG6, also known as GPR126, is a member of the adhesion G protein-coupled receptor (aGPCR) family that plays crucial roles in various biological processes, including cell adhesion, development, and signal transduction. Its unique structure, characterized by a large extracellular region, enables interactions with multiple ligands, which can influence cellular behavior and tissue homeostasis. Research has indicated that ADGRG6 is particularly important in the nervous system, contributing to myelination and neuronal differentiation. Dysregulation of ADGRG6 has been implicated in several pathological conditions, including neurological disorders and cancer. The study of recombinant ADGRG6 protein aims to elucidate its functional mechanisms and interaction partners, providing insights into its role in both normal physiology and disease. By understanding ADGRG6 signaling pathways and its downstream effects, researchers can explore potential therapeutic targets for conditions associated with its dysfunction. Furthermore, the production of recombinant ADGRG6 enables in vitro experiments to investigate its binding affinities, signaling cascades, and effects on various cell types, laying the groundwork for future advancements in targeted therapies and drug development. Overall, ADGRG6 represents a promising avenue for therapeutic intervention due to its critical involvement in cellular processes and disease pathology.
