Cat: PA1000-220DB

Recombinant Human ARL14 Protein,His

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Analytical Data

  • Gene name

    ARL14

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ARL14;ARF7;ADP-ribosylation factor-like Protein 14

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9BZQ6

  • Expression Region

    1-192aa

  • AA Sequence

    MGSSHHHHHH SSGLVPRGSH MGSLGSKNPQ TKQAQVLLLG LDSAGKSTLL YKLKLAKDIT TIPTIGFNVE MIELERNLSL TVWDVGGQEK MRTVWGCYCE NTDGLVYVVD STDKQRLEES QRQFEHILKN EHIKNVPVVL LANKQDMPGA LTAEDITRMF KVKKLCSDRN WYVQPCCALT GEGLAQGFRK LTGFVKSHMK SRGDTLAFFK QN

  • Molecular Weight

    24 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

The ARL14 protein, a member of the Arf (ADP-ribosylation factor) family, plays a crucial role in cellular processes such as membrane trafficking, cytoskeletal dynamics, and signal transduction. Recent studies have highlighted its involvement in regulating the actin cytoskeleton and maintaining cell shape, which is essential for various cellular functions and processes including migration, division, and differentiation. Dysregulation of ARL14 has been linked to various diseases, including cancer and neurodegenerative disorders, making it a potential target for therapeutic interventions. Given the increasing interest in the molecular mechanisms behind cell behavior, researchers have focused on generating recombinant ARL14 proteins to study their biochemical properties, interactions with other proteins, and roles in cellular pathways. This research not only aims to elucidate the specific functions of ARL14 in health and disease but also seeks to develop novel strategies for manipulating its activity, which could have significant implications for biomedical applications. By employing techniques such as biochemistry, cell biology, and structural biology, scientists are working towards a comprehensive understanding of ARL14's molecular mechanisms and its impact on cellular homeostasis.

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