Analytical Data
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Gene name
ARHGAP19
- Application
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Alternative Names
BRG1-associated factor 47 ;BAF47Integrase interactor 1 protein;SNF5 homolog ;hSNF5
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q12824
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Expression Region
1-494aa
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Molecular Weight
60.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ARHGAP19 is a member of the Rho GTPase-activating protein family, which plays a critical role in regulating the signaling pathways mediated by Rho GTPases. These pathways are essential for various cellular processes, including cytoskeletal dynamics, cell migration, and proliferation. Recent studies have implicated ARHGAP19 in multiple biological functions, particularly in neuronal development and function, suggesting its potential involvement in neurological disorders. Its specific activity in modulating Rho GTPase signaling makes it a key player in the pathways that govern cell shape and movement, which are particularly important during neural development. Furthermore, dysregulation of ARHGAP19 has been linked to various diseases, including cancer and neurodegenerative conditions, highlighting its importance as a potential therapeutic target. The recombinant expression of ARHGAP19 allows for in-depth biochemical and functional analyses, paving the way for understanding its mechanism of action and its role in health and disease. Overall, research into ARHGAP19 and its recombinant protein is crucial for deciphering its functions and potential implications in therapeutic contexts.
