Analytical Data
-
Gene name
DISP1
- Application
-
Alternative Names
DISP1；DISPA；Protein dispatched homolog 1
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q96F81
-
Expression Region
全长
-
AA Sequence
full
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DISP1, or Dispatched RND Transporter 1, is a crucial protein involved in the transport of holophosphates, particularly the lipid-modified morphogen Sonic Hedgehog (Shh), which plays a vital role in embryonic development and tissue patterning. The research background of DISP1 focuses on its significance in developmental biology, as the proper distribution of Shh is essential for organizing various cell types and structures during embryogenesis. Dysregulation of DISP1 can lead to developmental disorders and has been implicated in various diseases, including cancers. Investigating DISP1 through recombinant protein studies enhances our understanding of its structural and functional roles, mechanisms of action, and interaction with other cellular components. Recent advances in biotechnology have allowed for the production of recombinant DISP1 proteins, enabling detailed analyses of their biochemical properties and functional interactions. This research may provide insights into the therapeutic potential of targeting DISP1 pathways in various diseases, thereby opening new avenues for treatment strategies in developmental and pathological contexts. Understanding the role of DISP1 at the molecular level is crucial for uncovering the complexities of morphogen transport and its implications for health and disease.
