Analytical Data
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基因名
Ptger4
- Application
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别名
(PGE receptor EP4 subtype)(PGE2 receptor EP4 subtype)(Prostanoid EP4 receptor)
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种属
Mouse
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表达系统
E. coli
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标签
Tag Free
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P32240
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表达区间
361-513aa
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分子量
16.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of Ptger4 recombinant protein primarily revolves around its role as a receptor for prostaglandin E2 (PGE2), which is a significant lipid compound involved in various physiological processes, including inflammation, immune response, and tissue homeostasis. Ptger4, also known as the prostaglandin E receptor 4, is part of the E series of prostaglandin receptors and exhibits a unique expression pattern in different tissues, contributing to diverse biological functions. Research has shown that Ptger4 mediates the actions of PGE2 in several contexts, including pain modulation, reproductive functions, and cardiovascular health. Given the receptor’s involvement in pathophysiological conditions such as cancer, cardiovascular diseases, and chronic inflammatory diseases, it has garnered attention as a potential therapeutic target. The generation of Ptger4 recombinant protein enables researchers to conduct detailed studies on its signaling mechanisms, ligand specificity, and therapeutic implications. By exploring the structure and function of this receptor, scientists aim to develop novel drug strategies that can modulate its activity, ultimately leading to improved treatments for diseases associated with aberrant PGE2 signaling. Understanding the biological roles and therapeutic potential of Ptger4 can pave the way for innovative approaches in personalized medicine, particularly in managing diseases characterized by inflammation and immune dysregulation. Additionally, the recombinant protein can serve as a valuable tool for elucidating further molecular pathways and interactions that govern the receptor's functions, thereby enhancing our overall understanding of prostaglandin biology in health and disease.












