Analytical Data
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基因名
ACE
- Application
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别名
ACE;DCP;DCP1;Angiotensin-converting enzyme
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种属
Human
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表达系统
E. coli
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标签
N-terminal His Tag
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P12821
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表达区间
30-336aa
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氨基酸序列
LDPGLQPGNFSADEAGAQLFAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQ EEAALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRIIGAVRTLGSANLPLAKR QQYNALLSNMSRIYSTAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEG WHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQ QLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVP FPDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELS
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分子量
38.4kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Identification
Protein Description
The study of ACE (angiotensin-converting enzyme) recombinant proteins has gained significant traction due to the pivotal role of ACE in the renin-angiotensin system, which regulates blood pressure and fluid balance. Discovered in the 1970s, ACE converts angiotensin I into the active vasoconstrictor angiotensin II, thus influencing cardiovascular function and homeostasis. Abnormal ACE activity has been linked to various health conditions, including hypertension, heart failure, and diabetic complications. Researchers have increasingly focused on ACE recombinant proteins to better understand its structure and function, as well as to explore therapeutic interventions. The ability to produce ACE in a recombinant form allows for detailed studies of its enzymatic activity, substrate specificity, and potential inhibitors, which are critical for drug development. Furthermore, recombinant ACE proteins can be utilized in diagnostic assays and in the characterization of angiotensin peptides, enhancing our understanding of their physiological and pathophysiological roles. The emergence of biotechnological tools and techniques has propelled the advancement of ACE studies, facilitating the development of novel ACE-targeted therapies and improving our understanding of cardiovascular diseases on a molecular level. This research not only aims to optimize treatment strategies for existing cardiovascular disorders but also holds promise for innovative approaches to preventive medicine and personalized healthcare solutions.












