Analytical Data
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基因名
ADH6
- Application
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别名
ADH6；Alcohol dehydrogenase 6
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P28332-2
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表达区间
1-375aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSHMSTTGQVIRCKAAILWKPGAPFSIEE VEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLDLLYPTILGHEGAGIVE SIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSD GTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCG FSTGFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVN KEKFKKAQELGATECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVL AAALASCNESYGVCVVVGVLPASVQLKISGQLFFSGRSLKGSVFGGWK SRQHIPKLVADY MAEKLNLDPLITHTLNLDKINEAVELMKTGKCIRCI LLL
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分子量
42 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ADH6, or alcohol dehydrogenase 6, is a member of the alcohol dehydrogenase (ADH) superfamily, which plays a crucial role in the metabolism of endogenous and exogenous alcohols. This enzyme catalyzes the oxidation of alcohols to aldehydes, and its activity can influence various biochemical pathways, including those related to drug metabolism and alcohol detoxification. Research on ADH6 has gained significance due to its potential roles in alcohol-related disorders, where variations in ADH genes can affect an individual's propensity to develop alcohol dependence or other metabolic disorders. Additionally, ADH6 has been implicated in the metabolism of certain pharmaceuticals, which may impact therapeutic efficacy and safety. The recombinant expression of ADH6 in heterologous systems allows for extensive biochemical characterization, enabling researchers to investigate its enzymatic properties, substrate specificity, and regulatory mechanisms. Understanding the structure and function of ADH6 can facilitate the development of targeted therapies for alcohol-related conditions and enhance our comprehension of metabolic processes involving alcohols. Consequently, ADH6 represents a captivating target for investigations into alcohol metabolism and its implications in human health.
