Analytical Data
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Gene name
ACSF2
- Application
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Alternative Names
ACSF2；Medium-chain acyl-CoA ligase ACSF2. mitochondrial
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96CM8
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Expression Region
42-615aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSLSSREVD RMVSTPIGGL SYVQGCTKKH LNSKTVGQCL ETTAQRVPER EALVVLHEDV RLTFAQLKEE VDKAASGLLS IGLCKGDRLG MWGPNSYAWV LMQLATAQAG IILVSVNPAY QAMELEYVLK KVGCKALVFP KQFKTQQYYN VLKQICPEVE NAQPGALKSQ RLPDLTTVIS VDAPLPGTLL LDEVVAAGST RQHLDQLQYN QQFLSCHDPI NIQFTSGTTG SPKGATLSHY NIVNNSNILG ERLKLHEKTP EQLRMILPNP LYHCLGSVAG TMMCLMYGAT LILASPIFNG KKALEAISRE RGTFLYGTPT MFVDILNQPD FSSYDISTMC GGVIAGSPAP PELIRAIINK INMKDLVVAY GTTENSPVTF AHFPEDTVEQ KAESVGRIMP HTEARIMNME AGTLAKLNTP GELCIRGYCV MLGYWGEPQK TEEAVDQDKW YWTGDVATMN EQGFCKIVGR SKDMIIRGGE NIYPAELEDF FHTHPKVQEV QVVGVKDDRM GEEICACIRL KDGEETTVEE IKAFCKGKIS HFKIPKYIVF VTNYPLTISG KIQKFKLREQ MERHLNL
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Molecular Weight
66 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ACSF2 (acyl-CoA synthetase family member 2) is an enzyme that plays a crucial role in fatty acid metabolism and has garnered significant interest in recent years due to its potential implications in various biological processes and diseases. Research has shown that ACSF2 is involved in the activation of long-chain fatty acids, facilitating their conversion into acyl-CoA derivatives, which are essential for lipid synthesis, energy production, and signal transduction. Mutations or dysregulation of ACSF2 have been linked to metabolic disorders and may influence the development of conditions such as obesity, diabetes, and cardiovascular diseases. The recombinant expression of ACSF2 enables researchers to investigate its enzymatic properties, substrate specificity, and regulatory mechanisms in detail. Understanding the structure-function relationship of ACSF2 through the study of its recombinant protein can provide insights into its biological roles and the molecular basis of associated pathologies. Additionally, exploring ACSF2's potential as a therapeutic target offers promising avenues for developing interventions aimed at mitigating metabolic diseases. Overall, ACSF2 remains a topic of considerable interest in metabolic research, and its study is crucial for elucidating the complexities of lipid metabolism and its impact on human health.
