Analytical Data
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Gene name
Pcp4
- Application
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Alternative Names
Brain-specific antigen PCP-4 (Brain-specific polypeptide PEP-19) (Purkinje cell protein 4)
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Species
Mouse
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P63054
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Expression Region
1-62aa
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Molecular Weight
14.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PCP4 (Purkinje Cell Protein 4) is a neuron-specific protein predominantly expressed in Purkinje cells of the cerebellum, playing a critical role in neuronal function and signaling. Research into PCP4 has garnered attention due to its involvement in various neurological disorders, including spinocerebellar ataxia and certain types of epilepsy. The protein is known to interact with calcium signaling pathways, impacting synaptic plasticity and neurotransmitter release. Given its unique expression pattern and functional significance, recombinant PCP4 has become a valuable tool for studying its biological activities and mechanisms in cellular models. The production of PCP4 as a recombinant protein facilitates in-depth investigations into its structure-function relationship and potential therapeutic applications. Additionally, understanding PCP4's role in neural circuits may offer insights into the broader mechanisms of cerebellar function and its implication in disease states, highlighting the necessity for continued research in this area.
