Analytical Data
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基因名
Otop1
- Application
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别名
Otopetrin-1
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种属
Mouse
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q80VM9
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表达区间
1-600aa
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分子量
68.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Otop1, a member of the Otopetrin family, is a crucial protein involved in the sensory perception of taste and the function of the inner ear in vertebrates. Research has highlighted its role in the mechanotransduction processes of sensory cells, allowing organisms to perceive environmental stimuli. Originally identified in zebrafish, Otop1 has been linked to the development and functioning of otolith organs, which are responsible for balance and spatial orientation. Studies have shown that mutations in the Otop1 gene can lead to hearing impairments and vestibular disorders, emphasizing its significance in auditory and balance systems. The recombinant Otop1 protein has become a focus of interest due to its potential applications in gene therapy and regenerative medicine, as well as in understanding the molecular mechanisms underlying hearing and balance disorders. By producing and characterizing recombinant Otop1, researchers aim to elucidate its structure-function relationships and explore its interactions with other cellular components, thereby gaining insights into the pathways involved in auditory and vestibular functions. As the field of sensory biology progresses, the study of Otop1 and its recombinant forms may pave the way for innovative therapeutic strategies for patients suffering from sensory loss.
