Analytical Data
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基因名
iagB
- Application
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别名
iagB; STM2877Invasion protein IagB
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种属
Salmonella typhimurium
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P0CL15
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表达区间
20-160aa
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分子量
32 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IagB, a protein found in certain pathogenic bacteria, plays a crucial role in the regulation of virulence and pathogenicity. Research on IagB has gained attention due to its involvement in bacterial responses to environmental stresses, which can influence infectious processes. Its function is linked to the modulation of bacterial signaling pathways, particularly those related to the type III secretion system (T3SS), a key mechanism through which many bacteria inject effector proteins into host cells, facilitating infection. Understanding the structure and function of IagB is essential for unraveling the molecular mechanisms of bacterial virulence. Additionally, IagB represents a potential target for novel therapeutic strategies aimed at combating bacterial infections, as inhibiting its activity could weaken the virulence of pathogenic strains. Advances in recombinant protein technology allow for the production and characterization of IagB, enabling detailed studies of its biochemical properties and interactions with other cellular components. Consequently, IagB not only serves as a significant focus of study within microbiology and infectious diseases but also holds promise for informing the development of innovative antimicrobial agents. As researchers continue to elucidate the various roles of IagB within pathogenic bacteria, it may contribute to the broader understanding of bacterial adaptation and survival strategies in hostile environments.












