Analytical Data
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Gene name
Plk2
- Application
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Alternative Names
Polo-like kinase 2 Serine/threonine-protein kinase SNK Serum-inducible kinase
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Species
Mouse
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P53351
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Expression Region
1-682aa
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Molecular Weight
85.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLK2 (Polo-like kinase 2) is a serine/threonine kinase that plays a crucial role in various cellular processes, including cell cycle regulation, neuronal function, and signaling pathways related to stress responses. Its dysregulation has been implicated in several pathological conditions, including cancer and neurodegenerative diseases. The study of PLK2 recombinant proteins has gained attention due to their potential as therapeutic targets and tools for understanding PLK2's functional mechanisms. By producing PLK2 in a recombinant form, researchers can elucidate its biochemical properties, substrate interactions, and regulatory mechanisms, which are essential for deciphering its role in cellular physiology. Moreover, recombinant PLK2 proteins can facilitate high-throughput screening for small-molecule inhibitors or activators, contributing to the development of novel therapeutic agents. Understanding PLK2's function at the molecular level is vital for advancing our knowledge of its contributions to cell biology and pathology, thereby opening avenues for innovative treatment strategies in diseases associated with PLK2 dysfunction.
