Analytical Data
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Gene name
R497Q
- Application
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Alternative Names
INN: Alteplase INN: Reteplase
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Species
Human
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Source
Baculovirus
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P00750
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Expression Region
36-562aa(R497Q)
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Molecular Weight
62.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The R497Q recombinant protein has garnered significant attention in the field of molecular biology due to its potential implications in understanding the mechanisms underlying certain diseases, particularly those linked to genetic mutations. The R497Q variant is a specific single nucleotide polymorphism (SNP) in a gene associated with various cellular functions, and its alteration may influence protein structure and function, leading to altered biological pathways. Research studies have indicated that this mutation could be related to conditions such as cardiovascular diseases and certain types of cancer. By generating recombinant R497Q protein, researchers aim to investigate its structural characteristics, biochemical properties, and interactions with other molecules. This research is vital for elucidating the role of the R497Q variant in disease mechanisms and may ultimately contribute to the development of targeted therapies or diagnostic tools. Furthermore, understanding how this specific mutation affects protein activity can provide insights into broader genetic influences on health and disease, making the study of the R497Q recombinant protein a valuable area of research in the quest to advance precision medicine.
