Analytical Data
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Gene name
ZIC4
- Application
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Alternative Names
Zinc finger protein of the cerebellum 4
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Species
Human
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Source
E. coli
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Tag
N- His & C- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N9L1
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Expression Region
1-334aa
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Molecular Weight
39.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The ZIC4 gene, a member of the Zinc Finger of the Cerebellum (ZIC) family, plays a crucial role in the regulation of embryonic development and neural differentiation. Previous studies have shown that ZIC4 is involved in the development of the central nervous system, particularly in the cerebellum, and is linked to various neurological disorders. Researchers have been interested in investigating the protein's structure and function to understand its role in neuronal differentiation and possible implications in disease mechanisms. Recombining ZIC4 protein provides a valuable tool to study its interactions with other cellular pathways and protein partners in vitro and in vivo. This research is essential not only for elucidating ZIC4's biological functions but also for its potential application in gene therapy and regenerative medicine, where modulating ZIC4 function could offer therapeutic strategies for neurodevelopmental disorders. Understanding how ZIC4 operates at the molecular level can pave the way for innovative approaches to treat conditions related to neural development and function. As we decipher the complexities of the ZIC4 protein's role in neural dynamics, we can foster advancements in developmental biology and explore novel avenues for clinical intervention.
