Analytical Data
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基因名
ZIC4
- Application
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别名
Zinc finger protein of the cerebellum 4
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种属
Human
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表达系统
E. coli
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标签
N- His & C- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N9L1
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表达区间
1-334aa
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分子量
39.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The ZIC4 gene, a member of the Zinc Finger of the Cerebellum (ZIC) family, plays a crucial role in the regulation of embryonic development and neural differentiation. Previous studies have shown that ZIC4 is involved in the development of the central nervous system, particularly in the cerebellum, and is linked to various neurological disorders. Researchers have been interested in investigating the protein's structure and function to understand its role in neuronal differentiation and possible implications in disease mechanisms. Recombining ZIC4 protein provides a valuable tool to study its interactions with other cellular pathways and protein partners in vitro and in vivo. This research is essential not only for elucidating ZIC4's biological functions but also for its potential application in gene therapy and regenerative medicine, where modulating ZIC4 function could offer therapeutic strategies for neurodevelopmental disorders. Understanding how ZIC4 operates at the molecular level can pave the way for innovative approaches to treat conditions related to neural development and function. As we decipher the complexities of the ZIC4 protein's role in neural dynamics, we can foster advancements in developmental biology and explore novel avenues for clinical intervention.
