Analytical Data
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Gene name
NUDT2
- Application
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Alternative Names
Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P50583
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Expression Region
1-147aa
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Molecular Weight
43.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NUDT2 is a member of the Nudix hydrolase family, which is known for its role in hydrolyzing a variety of nucleotide derivatives, playing important roles in cellular metabolism and signaling. Research into NUDT2 has garnered attention due to its potential implications in the regulation of cellular stress responses and its involvement in various diseases. Specifically, NUDT2 hydrolyzes uridine diphosphate (UDP)-type metabolites, influencing the balance of nucleotide pools and thus impacting cellular functions such as cardiovascular health, immune responses, and metabolic disorders. Abnormalities in NUDT2 expression and activity have been linked to increased susceptibility to oxidative stress and inflammatory responses, which are pivotal in the pathogenesis of several diseases, including cancer and neurodegenerative disorders. By studying the structure, function, and regulation of NUDT2, researchers aim to elucidate its precise roles in health and disease, providing insights into potential therapeutic interventions. This research is expected to contribute to a deeper understanding of nucleotide metabolism and its broader implications in human health, paving the way for novel strategies in disease prevention and treatment.
