Analytical Data
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基因名
PCOLCE2
- Application
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别名
Procollagen COOH-terminal proteinase enhancer 2 Short name: PCPE-2 Short name: Procollagen C-proteinase enhancer 2
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UKZ9
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表达区间
24-415aa
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分子量
59.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PCOLCE2, or procollagen C-endopeptidase enhancer 2, is a key protein involved in the regulation of collagen synthesis and maturation, playing a crucial role in extracellular matrix (ECM) remodeling. Given its significant function in connective tissue biology, PCOLCE2 has garnered attention in the context of various diseases, including fibrotic disorders, cardiovascular diseases, and cancer. Research has demonstrated that alterations in PCOLCE2 expression can affect collagen deposition and ECM integrity, highlighting its potential as a therapeutic target. Additionally, understanding the molecular mechanisms underlying PCOLCE2 function can provide insights into tissue repair and regeneration processes. The production of recombinant PCOLCE2 proteins is essential for in-depth studies aimed at deciphering its role in collagen dynamics and the impact of its dysregulation in pathological conditions. This research not only seeks to elucidate the biochemical pathways associated with PCOLCE2 but also aims to explore its potential as a biomarker for disease progression or therapeutic response, paving the way for novel interventions in ECM-related diseases.
