Analytical Data
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基因名
IZUMO1R
- Application
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别名
Folate receptor 4 (Folate receptor delta) (FR-delta) (IZUMO1 receptor protein JUNO) (FOLR4) (JUNO)
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A6ND01
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表达区间
20-250aa
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分子量
32.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IZUMO1R, also known as the Izumo sperm-egg fusion protein receptor, is an essential component in the process of fertilization. It plays a critical role in sperm-egg recognition and fusion, facilitating successful reproduction. The research surrounding IZUMO1R has gained significant attention due to its implications in infertility, particularly as abnormalities in IZUMO1R function may lead to reproductive challenges. Recent studies have focused on characterizing the structural and functional properties of this receptor, including its interaction with the Izumo1 protein on sperm. Recombinant IZUMO1R protein has been produced to further explore these interactions and to potentially develop therapeutic strategies for infertility treatments. Understanding the mechanisms underlying IZUMO1R's role could not only enhance our knowledge of fertilization but also inform the development of diagnostic tools and targeted therapies aimed at resolving male and female infertility. This research is particularly crucial given the increasing prevalence of reproductive disorders worldwide. Advances in this area could potentially lead to groundbreaking techniques in assisted reproductive technologies, thus benefiting couples facing challenges in conceiving.
