Analytical Data
-
基因名
FBXL18
- Application
-
别名
F-box and leucine-rich repeat protein 18
-
种属
Human
-
表达系统
E. coli
-
标签
N- His-SUMO
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q96ME1
-
表达区间
1-365aa
-
分子量
56.2 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FBXL18, a member of the F-box protein family, plays a crucial role in the ubiquitin-proteasome system, which is essential for protein degradation and regulation of various cellular processes. Research has indicated that FBXL18 is involved in the cell cycle, apoptosis, and differentiation, making it a significant focus in cancer biology and developmental studies. Its unique structural features allow it to interact with specific substrates, leading to targeted ubiquitination and proteolysis. Recent studies have linked aberrant FBXL18 expression to various malignancies, suggesting its potential as a biomarker or therapeutic target. Understanding the molecular mechanisms underlying FBXL18's function may provide insights into tumorigenesis and other pathological conditions. Furthermore, the characterization of FBXL18 as a recombinant protein paves the way for further functional assays, allowing researchers to explore its interactions and regulatory pathways in detail. This research can enhance our understanding of cellular homeostasis and may lead to novel therapeutic strategies for diseases where FBXL18 is implicated.
