Analytical Data
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基因名
DOK5
- Application
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别名
Downstream of tyrosine kinase 5Insulin receptor substrate 6 ;IRS-6 ;IRS6
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9P104
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表达区间
1-198aa
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分子量
38.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of DOK5 (Downstream of Kinase 5) recombinant protein has gained considerable attention in recent years due to its critical role in cellular signaling pathways. DOK5 is part of the DOK family, which is characterized by the presence of a Phosphotyrosine Binding (PTB) domain that enables interactions with various receptor tyrosine kinases. Research indicates that DOK5 acts as a scaffold protein, facilitating the assembly of signaling complexes that regulate crucial cellular processes such as proliferation, differentiation, and survival. Dysregulation of these pathways has been implicated in several diseases, including cancers and metabolic disorders. By producing recombinant DOK5 protein, scientists aim to elucidate its molecular interactions and functional roles in signaling pathways, with the potential to identify novel therapeutic targets. This research is particularly significant given the increasing understanding of the importance of protein-protein interactions in signal transduction and the complexity of cellular responses. Furthermore, recombinant DOK5 can be utilized in various applications, including structure-function studies, drug discovery, and as a biomarker in disease states. Overall, the exploration of DOK5 recombinant protein not only enhances our understanding of fundamental biological processes but also opens avenues for therapeutic advancements in related pathologies.
