Analytical Data
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基因名
CSRP3
- Application
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别名
Cardiac LIM protein;Cysteine-rich protein 3 ;CRP3LIM domain protein, cardiacMuscle LIM protein
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P50461
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表达区间
1-194aa
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分子量
37 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CSRP3 (Cysteine and Serine-rich Protein 3), also known as muscle LIM protein (MLP), plays a crucial role in muscle development and function, particularly in cardiac and skeletal muscles. It is associated with the structural integrity of the sarcomere, the fundamental unit of muscle contraction. Studies have shown that CSRP3 acts as a scaffold for signaling molecules and transcription factors, contributing to the regulation of gene expression and cellular responses to mechanical stress. Mutations in the CSRP3 gene have been linked to various cardiomyopathies, highlighting its importance in maintaining heart health. The recombinant protein form of CSRP3 is a valuable tool for investigating its molecular functions and interactions in vitro. Researchers aim to produce this protein through recombinant DNA technology for further studies, including structural analysis, protein-protein interactions, and functional assays. Understanding the precise role of CSRP3 in muscle signaling pathways can provide insights into the mechanisms underlying muscular diseases and lead to potential therapeutic strategies. As such, the development of CSRP3 recombinant protein is fundamental for advancing our knowledge of muscle biology and improving approaches to treat related disorders.
