Analytical Data
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Gene name
HTR2B
- Application
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Alternative Names
Serotonin receptor 2B
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P41595
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Expression Region
1-481aa
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Molecular Weight
70.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The HTR2B gene, which encodes the serotonin receptor 2B, plays a crucial role in various physiological processes, including mood regulation, appetite control, and vascular function. Research into HTR2B has gained significant attention due to its implications in psychiatric disorders such as depression, anxiety, and schizophrenia, as well as its involvement in cardiovascular diseases. The receptor is known to be a G-protein-coupled receptor (GPCR), which makes it a vital target in pharmacology for developing therapeutic agents. Recombining HTR2B into functional proteins enables scientists to study its structure, signaling pathways, and interactions with various ligands. Understanding the functional dynamics of HTR2B can reveal insights into the receptor's role in neuronal communication and its potential as a therapeutic target. Furthermore, the recombined protein can be employed in high-throughput screening assays for drug discovery, thereby accelerating the search for safe and effective treatments for conditions associated with serotonergic dysregulation. As research continues to unveil the complexities of serotonin signaling, the importance of HTR2B reorganization in revealing novel treatment strategies remains a significant area of focus in neuroscience and pharmacology.
