Analytical Data
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Gene name
Itgax
- Application
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Alternative Names
CD11 antigen-like family member C Leukocyte adhesion glycoprotein p150,95 alpha chain Leukocyte adhesion receptor p150,95 CD_antigen: CD11c
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Species
Mouse
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Source
Baculovirus
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Tag
N- MBP & C- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9QXH4
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Expression Region
20-1116aa
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Molecular Weight
165.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Itgax, also known as integrin alpha X, is a member of the integrin family of proteins, which play crucial roles in cell adhesion, migration, and signaling processes. Itgax is predominantly expressed in immune cells, particularly in monocytes, macrophages, and dendritic cells, where it is involved in immune responses and inflammatory processes. Research on Itgax has gained momentum due to its association with various diseases, including autoimmune disorders, cancer, and chronic inflammatory conditions. The reconstitution of Itgax in laboratory settings allows scientists to study its structural and functional properties, providing insights into its role in cell communication and tissue homeostasis. Understanding Itgax's mechanisms could lead to novel therapeutic strategies targeting immune modulation and improving treatment outcomes for related diseases. Additionally, the development of Itgax-based biomolecules holds promise for advancing targeted therapies and enhancing vaccine efficacy. As such, this protein remains a significant focus in immunological and biomedical research, highlighting the importance of elucidating its functional dynamics in health and disease.
