Cat: IPD-X39664

Recombinant Human TAB2 Protein (Baculovirus),His & Myc

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Analytical Data

  • 基因名

    TAB2

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2) (KIAA0733) (MAP3K7IP2)

  • 种属

    Human

  • 表达系统

    Baculovirus

  • 标签

    N- His & C- Myc

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9NYJ8

  • 表达区间

    401-693aa

  • 分子量

    37.1 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

TAB2 (TAK1-binding protein 2) is an essential regulatory protein involved in various cellular signaling pathways, particularly those related to inflammation and stress response. It plays a crucial role in the activation of the MAPK (mitogen-activated protein kinases) pathway, mediating the signaling of cytokines and growth factors. The study of TAB2 recombinants has gained attention due to its involvement in diverse physiological processes and its implications in various diseases, including cancer, autoimmune disorders, and neurodegenerative diseases. Understanding the structure and function of TAB2 may provide insights into its role in pathophysiology and could lead to the development of targeted therapeutic strategies. Recent advances in molecular biology techniques have facilitated the production of recombinant TAB2, enabling researchers to investigate its mechanisms of action in detail. By characterizing TAB2's interactions with other proteins and elucidating its functional domains, scientists aim to uncover its potential as a therapeutic target and to inform strategies for modulating its activity in disease contexts. The ongoing research on TAB2 not only enhances our understanding of intracellular signaling networks but also opens avenues for novel interventions in diseases where dysregulation of these pathways contributes to pathological conditions.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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