Analytical Data
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Gene name
RAD54L2
- Application
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Alternative Names
SRISNF2L; Helicase ARIP4; Androgen receptor-interacting protein 4
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y4B4
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Expression Region
Ala638~Ser837
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Molecular Weight
27kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAD54L2, a member of the RAD54 protein family, plays a crucial role in DNA repair and homologous recombination processes. This protein is particularly interesting due to its involvement in maintaining genomic stability and responding to DNA damage, which are vital for cellular health and preventing cancer development. The study of RAD54L2 is important because alterations in its function or expression may contribute to various diseases, including cancer. Researchers have focused on understanding the molecular mechanisms by which RAD54L2 facilitates homologous recombination, particularly its interactions with other proteins in the DNA repair machinery. Investigations have also revealed that RAD54L2 may have distinct features compared to its closely related paralogs, which could provide insights into its unique functions in the repair of DNA double-strand breaks. Understanding RAD54L2's role in the context of the broader DNA repair landscape may lead to the identification of novel therapeutic targets for cancer treatment and enhance our comprehension of genetic stability mechanisms. As the need for targeted cancer therapies increases, elucidating the function and regulatory pathways of RAD54L2 becomes essential for advancing knowledge in cancer biology and developing potential interventions.










