Analytical Data
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Gene name
SPIN3
- Application
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Alternative Names
Spindlin-like protein 3
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5JUX0
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Expression Region
Met1~Leu77
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Molecular Weight
16kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SPIN3, a member of the SPIN family of proteins, has garnered significant attention in recent years due to its potential role in various cellular processes and its implications in cancer biology. Emerging evidence suggests that SPIN3 is involved in the regulation of gene expression, cellular differentiation, and responses to stress, which positions it as a key player in maintaining cellular homeostasis. Its expression patterns have been linked to several malignancies, leading researchers to investigate its functional mechanisms and interaction networks. Studies have indicated that SPIN3 might act as a transcriptional regulator, influencing pathways critical for cell proliferation and survival. Understanding the structure and function of SPIN3, particularly through the development of recombinant proteins, allows scientists to explore its biological roles in a controlled environment. This research is crucial for elucidating the molecular underpinnings of diseases associated with SPIN3 dysregulation and holds promise for target discovery in therapeutic interventions. By employing advanced techniques in molecular biology and protein engineering, researchers aim to characterize SPIN3 interactions and its impact on oncogenic pathways, which could pave the way for novel diagnostic and treatment strategies in oncology. Furthermore, the ability to produce SPIN3 as a recombinant protein facilitates high-throughput screening assays and structural studies, thus accelerating the understanding of its functional properties and potential as a biomarker or therapeutic target in cancer and other related diseases.
