Analytical Data
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Gene name
IRAK1BP1
- Application
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Alternative Names
AIP70; SIMPL; Signaling Molecule That Associates With The Mouse Pelle-Like Kinase
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5VVH5
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Expression Region
Met1~Leu260
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Molecular Weight
59kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IRAK1BP1 (Interleukin-1 receptor-associated kinase 1 binding protein 1) is a protein that has gained attention in recent years due to its role in the regulation of immune responses and its potential implications in various diseases, including cancer and autoimmune disorders. As a member of the IRAK family, IRAK1BP1 interacts with key signaling molecules involved in the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) pathways, which are crucial for the activation of innate immune responses. Research has indicated that IRAK1BP1 may play a pivotal role in modulating inflammatory signaling, thereby influencing the outcome of immune activation. Due to its significant involvement in immune regulation, scientists are increasingly interested in understanding the mechanisms underlying IRAK1BP1 function and its potential as a therapeutic target. Recombinant expression and purification of IRAK1BP1 have become essential for biophysical characterizations, functional assays, and the development of targeted treatments. By using recombinant protein studies, researchers aim to elucidate the structural and biological properties of IRAK1BP1, which may lead to novel strategies in managing diseases associated with dysregulated immune responses. Overall, the study of recombinant IRAK1BP1 holds promise for advancing our understanding of immune signaling pathways and their relevance to human health.
