Analytical Data
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基因名
PSMD9
- Application
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别名
Rpn4; p27; 26S proteasome regulatory subunit p27; 26S proteasome non-ATPase regulatory subunit 9
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O00233
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表达区间
Ser2~Arg223
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分子量
30kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PSMD9 (Proteasome 26S Subunit, Non-ATPase 9) is a crucial component of the 26S proteasome, which plays a vital role in protein degradation and cellular regulation. The proteasome itself is responsible for the ubiquitin-proteasome pathway, a major mechanism for controlling protein levels and functions, influencing various cellular processes such as the cell cycle, signal transduction, and response to stress. Research on PSMD9 has gained significance due to its implication in multiple biological pathways and diseases, including cancer and neurodegenerative disorders. Dysregulation of the proteasome system can lead to the accumulation of damaged or misfolded proteins, contributing to cellular dysfunction. Consequently, studying the structure, function, and regulation of PSMD9 recombinant protein is essential for understanding its role in proteasome activity and potential therapeutic targets. Advances in recombinant protein technology have facilitated the production and characterization of PSMD9, enabling researchers to investigate its interaction with other proteasome subunits and regulatory proteins. This knowledge may provide insights into the development of novel drugs that can modulate proteasome activity, offering potential therapeutic strategies for diseases associated with proteasome dysfunction. Overall, understanding the biology of PSMD9 and its role within the proteasome complex is crucial for advancing our knowledge of protein homeostasis and its impact on human health.
