Analytical Data
-
Gene name
ST14
- Application
-
Alternative Names
SNC19; HAI; MT-SP1; PRSS14; TADG15; Epithin; Matriptase; Prostamin; Membrane-type serine protease 1; Serine protease 14; Tumor-associated differentially-expressed gene 15
-
Species
Human
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
AAH30532.1
-
Expression Region
Arg607~Asn852
-
Molecular Weight
33kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ST14, also known as matriptase, is a type II transmembrane serine protease that plays a crucial role in various physiological processes, including skin homeostasis, wound healing, and tumor invasion. Its activity is tightly regulated, as aberrant regulation can lead to pathological conditions such as cancer progression and inflammatory diseases. Research into ST14 has revealed its involvement in the activation of other proteases and the modulation of various signaling pathways. Given its significant physiological roles, ST14 has become a target of interest in both basic research and therapeutic development. The recombinant ST14 protein is essential for studying its enzymatic functions, interactions, and regulatory mechanisms in vitro and in vivo. It also aids in exploring the molecular basis of ST14-related diseases and identifying potential inhibitors or modulators that could serve as novel therapeutic agents. Understanding ST14's structure and function at the molecular level is critical for developing targeted strategies to manage diseases associated with its dysregulation. With advancements in recombinant protein technology, the production and characterization of ST14 have expanded, providing valuable insights into its functional properties and potential clinical applications.
