Analytical Data
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基因名
GLTP
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简介
GLTP Protein is pivotal in facilitating the intermembrane transfer of diverse glycolipids, specifically catalyzing the transfer of various glycosphingolipids while excluding phospholipids. Its potential role in intracellular translocation of glucosylceramides underscores its significance in lipid metabolism. Notably, GLTP operates as a monomer in executing these lipid transfer activities. GLTP Protein, Human (HEK293, His) is the recombinant human-derived GLTP protein, expressed by HEK293 , with N-His labeled tag.
- Application
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别名
Glycolipid transfer protein; GLTP
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种属
Human
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表达系统
HEK293
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NZD2
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表达区间
M1-V209
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蛋白长度
Full Length
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GLTP (glycolipid transfer protein) plays a critical role in lipid metabolism and cellular signaling, making it a significant focus in biomedical research. It facilitates the transfer of glycolipids between membranes, contributing to various physiological processes including cell membrane dynamics, pathogen recognition, and signaling pathways. The disruption of GLTP function has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes, highlighting its importance in maintaining cellular homeostasis. Recent studies have shown that GLTP is involved in modulating immune responses and maintaining neuronal stability, which further underscores its therapeutic potential. The recombinant expression of GLTP provides a valuable tool for researchers to elucidate its functional mechanisms, investigate its interaction with other biomolecules, and explore its role in disease. By producing GLTP as a recombinant protein, scientists can analyze its structural and functional properties in vitro and in vivo, paving the way for the development of targeted therapies that could manipulate glycolipid transfer processes. This research is crucial not only for understanding the basic biology of GLTP but also for its potential applications in developing novel treatments for related diseases.
