Analytical Data
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基因名
PRSS2/Trypsin-2
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简介
PRSS2 Protein plays an important role in the metastasis and recurrence of multiple tumor types through its actions of destroying the ECM and activating MMPs. PRSS2/Trypsin-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PRSS2/Trypsin-2 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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别名
Trypsin-2; Anionic trypsinogen; Serine protease 2; Trypsin II; PRSS2; TRY2; TRYP2
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种属
Mouse
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q792Y6
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表达区间
F16-N246
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蛋白长度
Full Length of Mature Protein
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分子量
32 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PRSS2, also known as Trypsin-2, is a serine protease that plays a pivotal role in various physiological processes, including digestion, immune response, and embryogenesis. It is predominantly expressed in the pancreas, where it is crucial for the initial stages of protein digestion. Abnormalities in PRSS2 expression or activity have been implicated in several pathologies, including pancreatitis and pancreatic cancer, making it a target of interest for therapeutic interventions. Recent studies have focused on the recombinant production of PRSS2 to facilitate detailed investigations into its structure and function. By utilizing recombinant DNA technology, researchers can produce large quantities of PRSS2 for biochemical characterization, screening inhibitors, and exploring its role in disease mechanisms. Furthermore, the availability of purified PRSS2 protein can significantly enhance our understanding of its enzymatic properties and interactions with substrates and inhibitors. As a result, research on PRSS2 not only contributes to elucidating the fundamental aspects of protease biology but also holds promise for developing novel diagnostic and therapeutic strategies for diseases linked to dysregulated trypsin activity.
