Analytical Data
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基因名
MX2
- Application
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别名
MXB; Interferon-Regulated Resistance GTP-Binding Protein MXB; Second Interferon-Induced Protein p78
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P20592
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表达区间
Met1~Asp300
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分子量
40kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MX2, a member of the MX family of proteins, is an interferon-inducible protein that has garnered significant attention in virology and immunology due to its antiviral properties. First identified as a potent inhibitor of viral replication, MX2 has been shown to specifically target RNA viruses, including HIV and various influenza strains. Its mechanism of action involves the disruption of viral nucleoprotein and RNA interactions, effectively halting the viral lifecycle. Research has revealed that expression levels of MX2 correlate with enhanced antiviral responses, making it a crucial player in the innate immune system. Moreover, genetic variations in the MX2 gene have been associated with a range of diseases, further emphasizing its importance in human health. Recent studies have focused on understanding the molecular pathways regulating MX2 expression and its potential as a therapeutic target in viral infections. Given the global burden of infectious diseases, elucidating the role of MX2 in antiviral defense mechanisms could yield novel strategies for vaccine development and antiviral therapies.
