Analytical Data
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Gene name
MX2
- Application
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Alternative Names
MXB; Interferon-Regulated Resistance GTP-Binding Protein MXB; Second Interferon-Induced Protein p78
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P20592
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Expression Region
Met1~Asp300
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Molecular Weight
40kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MX2, a member of the MX family of proteins, is an interferon-inducible protein that has garnered significant attention in virology and immunology due to its antiviral properties. First identified as a potent inhibitor of viral replication, MX2 has been shown to specifically target RNA viruses, including HIV and various influenza strains. Its mechanism of action involves the disruption of viral nucleoprotein and RNA interactions, effectively halting the viral lifecycle. Research has revealed that expression levels of MX2 correlate with enhanced antiviral responses, making it a crucial player in the innate immune system. Moreover, genetic variations in the MX2 gene have been associated with a range of diseases, further emphasizing its importance in human health. Recent studies have focused on understanding the molecular pathways regulating MX2 expression and its potential as a therapeutic target in viral infections. Given the global burden of infectious diseases, elucidating the role of MX2 in antiviral defense mechanisms could yield novel strategies for vaccine development and antiviral therapies.
