Analytical Data
-
基因名
NLGN4X
-
简介
The NLGN4X protein is a cell surface protein involved in cell-cell interactions through neurotoxin family interactions. NLGN4X Protein, Human (HEK293, His) is the recombinant human-derived NLGN4X protein, expressed by HEK293 , with C-6*His labeled tag.
- Application
-
别名
Neuroligin-4 X-Linked; Neuroligin X; HNLX; NLGN4X; KIAA1260; NLGN4
-
种属
Human
-
表达系统
HEK293
-
标签
C-6*His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q8N0W4-1
-
表达区间
Q42-S676
-
氨基酸序列
QAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELS
-
蛋白长度
Extracellular Domain
-
分子量
95 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NLGN4X, a member of the neuroligin family, plays a significant role in synapse formation and function within the central nervous system. It is located on the X chromosome, and its mutations have been linked to neurodevelopmental disorders, including autism spectrum disorder (ASD). Research has shown that NLGN4X interacts with neurexins and other synaptic proteins, which are crucial for maintaining synaptic stability and plasticity. The study of NLGN4X recombinant proteins has gained traction as it provides insights into the molecular mechanisms underlying synaptic transmission and the pathogenic effects of its variants. By expressing and characterizing NLGN4X recombinant proteins, researchers aim to elucidate how specific mutations affect protein structure and function, leading to synaptic dysfunction associated with neurological disorders. This research not only enhances our understanding of synapse biology but also has potential implications in developing therapeutic strategies for treating disorders linked to NLGN4X dysregulation. Overall, the study of NLGN4X recombinant proteins is critical for advancing our knowledge of synaptic mechanisms and their roles in neurodevelopmental conditions.
