Analytical Data
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Gene name
ADAM22
- Application
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Alternative Names
MDC2; Disintegrin And Metalloproteinase Domain-Containing Protein 22; Metalloproteinase-Like,Disintegrin-Like,And Cysteine-Rich Protein 2
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9P0K1
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Expression Region
Leu370~Asn582
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Molecular Weight
30kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ADAM22, a member of the ADAM (A Disintegrin and Metalloproteinase) family, is a crucial protein implicated in various physiological and pathological processes, particularly in the nervous system and muscle tissues. Research on ADAM22 has gained momentum due to its roles in cell adhesion, membrane fusion, and receptor interaction, which are vital in neurodevelopment and synaptic signaling. Studies have shown that ADAM22 is involved in synapse formation and maintenance, influencing cognitive functions and potentially contributing to neurodegenerative diseases. Additionally, its expression has been linked to autoimmune conditions, highlighting its significance in immune responses. The recombinant production of ADAM22 protein enables detailed investigations into its structural and functional properties, facilitating the understanding of its mechanisms of action. By generating a high-purity, biologically active form of ADAM22, researchers aim to explore its interactions with various ligands and receptors, assess its enzymatic activity, and evaluate its potential as a therapeutic target. Consequently, the study of recombinant ADAM22 protein not only deepens our understanding of its biological roles but also provides insights for developing novel strategies to address neurological and autoimmune disorders.
