Analytical Data
-
Gene name
DAPP1
- Application
-
Alternative Names
BAM32; B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
-
Species
Mouse
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9QXT1
-
Expression Region
Met1~Lys280
-
Molecular Weight
36.0kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DAPP1, or Dual Adapter for Phosphotyrosine-binding 1, is a protein that plays a crucial role in various cellular signaling pathways, particularly those linked to immune responses and cell activation. Its primary function involves binding to phosphorylated tyrosine residues on target proteins, which is essential for transmitting signals initiated by receptor activation. Research into DAPP1 has gained traction due to its involvement in hematopoietic cell development and its potential implications in diseases such as cancer and autoimmune disorders. Specifically, studies have demonstrated that DAPP1 regulates the activation of T cells and B cells, modulating immune responses and maintaining cellular homeostasis. Additionally, alterations in DAPP1 expression or function have been correlated with the progression of immune-related diseases, thus positioning it as a potential biomarker or therapeutic target. The recombinant expression of DAPP1 provides a platform for elucidating its molecular mechanisms and interactions within signaling pathways, as well as for screening potential inhibitors or modulators that could influence its activity in pathological conditions. Consequently, understanding DAPP1 at the molecular level could facilitate the development of novel strategies for the treatment of diseases where immune signaling is disrupted.
