Analytical Data
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Gene name
E2F2
- Application
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q14209
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Expression Region
Arg129~Tyr429
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Molecular Weight
68kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
E2F2, a member of the E2F transcription factor family, plays a critical role in regulating the cell cycle and is involved in the transcriptional activation of genes necessary for DNA synthesis and progression through the S phase. Research on E2F2 is particularly significant due to its dual function in promoting cell proliferation and its potential involvement in tumorigenesis. Dysregulation of E2F2 has been linked to various cancers, making it an interesting target for cancer therapy. Studies have shown that E2F2 can interact with other proteins and transcription factors, such as retinoblastoma (Rb) protein, which modulates its activity and stability. Furthermore, E2F2 not only participates in the control of cell cycle progression but also has implications in developmental processes and cellular differentiation. This multifaceted role suggests that understanding the mechanisms governing E2F2 function and regulation could provide insights into both normal cellular processes and pathological conditions. Ongoing research aims to elucidate the precise signaling pathways that regulate E2F2 activity and to explore its potential as a biomarker or therapeutic target in cancer treatment. Overall, the study of E2F2 is crucial for advancing our knowledge of cell cycle regulation, cancer biology, and potential therapeutic interventions.
