Analytical Data
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基因名
MAGEA4
- Application
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别名
(Cancer/testis antigen 1.4) (CT1.4) (MAGE-4 antigen) (MAGE-41 antigen) (MAGE-X2 antigen)
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种属
Human
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表达系统
HEK293
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标签
C- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P43358
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表达区间
1-317aa
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分子量
36.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MAGEA4, a member of the MAGE (Melanoma Antigen Gene) family, is a cancer-testis (CT) antigen predominantly expressed in various tumors while remaining silent in normal tissues except for the testis. The expression of MAGEA4 in cancer cells has garnered significant interest due to its potential role in the immune response, making it a promising target for cancer immunotherapy. Researchers have focused on the recombinant production of MAGEA4 to explore its biological properties and immunogenicity. By generating recombinant MAGEA4 protein, scientists aim to identify the epitopes recognized by T cells, facilitating the development of MAGEA4-based vaccines and immunotherapies. Additionally, studying the protein's structure and function can provide insights into tumor biology and the mechanisms of immune evasion employed by cancer cells. Overall, the investigation of MAGEA4 recombinant protein is crucial for advancing personalized cancer treatment strategies and improving patient outcomes in various malignancies.
