Analytical Data
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基因名
UROC1
- Application
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别名
Urocanase; Imidazolonepropionate hydrolase; Urocanate hydratase
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96N76
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表达区间
Thr551~Val631
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分子量
13kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
UROC1, a member of the UROD family, has garnered attention in recent years due to its potential role in renal pathophysiology and its implications in various kidney diseases. This recombinant protein has been identified as being involved in the regulation of uroporphyrin metabolism, which is crucial for maintaining normal heme synthesis and metabolic balance. Abnormalities in UROC1 expression and activity have been linked to conditions such as porphyrias and chronic kidney disease. Furthermore, its expression levels may serve as biomarkers for diagnosing renal dysfunction and evaluating disease progression. The pursuit of UROC1 recombinant protein research aims to elucidate its structural and functional properties, paving the way for the development of novel therapeutic strategies. Advanced techniques, such as protein engineering and structural biology, are being employed to investigate UROC1 interactions and signaling pathways, which could reveal new insights into its role within the renal context. As a result, understanding UROC1's function at the molecular level may not only enhance our comprehension of kidney diseases but also contribute to the advancement of targeted treatments, marking a significant step forward in renal medicine.












