Analytical Data
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Gene name
UROC1
- Application
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Alternative Names
Urocanase; Imidazolonepropionate hydrolase; Urocanate hydratase
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96N76
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Expression Region
Thr551~Val631
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Molecular Weight
13kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
UROC1, a member of the UROD family, has garnered attention in recent years due to its potential role in renal pathophysiology and its implications in various kidney diseases. This recombinant protein has been identified as being involved in the regulation of uroporphyrin metabolism, which is crucial for maintaining normal heme synthesis and metabolic balance. Abnormalities in UROC1 expression and activity have been linked to conditions such as porphyrias and chronic kidney disease. Furthermore, its expression levels may serve as biomarkers for diagnosing renal dysfunction and evaluating disease progression. The pursuit of UROC1 recombinant protein research aims to elucidate its structural and functional properties, paving the way for the development of novel therapeutic strategies. Advanced techniques, such as protein engineering and structural biology, are being employed to investigate UROC1 interactions and signaling pathways, which could reveal new insights into its role within the renal context. As a result, understanding UROC1's function at the molecular level may not only enhance our comprehension of kidney diseases but also contribute to the advancement of targeted treatments, marking a significant step forward in renal medicine.
