Recombinant Human MARCKS Protein，His & SUMO

MARCKS (Myristoylated Alanine-Rich C Kinase Substrate) is a key protein involved in various cellular processes, including cell motility, signaling, and cytoskeletal dynamics. Its significance lies in its ability to interact with membranes and cytoskeletal components, affecting processes such as cell adhesion and migration. The phosphorylation of MARCKS by protein kinase C (PKC) regulates its cellular functions, making it a critical component in the signaling cascades linked to growth factor responses and inflammation. Research has highlighted MARCKS's role in various pathological conditions, including cancer, where its expression levels and activity can influence tumor progression and metastasis. Additionally, MARCKS is implicated in neurological disorders due to its involvement in synaptic plasticity and neuronal development. Understanding the structural and functional aspects of MARCKS, particularly through the study of recombinant forms of the protein, can provide insights into its mechanistic roles and potential therapeutic targets. Recombinant MARCKS proteins are utilized for examining the interactions with other cellular molecules, facilitating the exploration of its functions in disease models. Overall, the investigation of MARCKS and its derivatives is crucial for unraveling the complex web of cellular signaling and offers promising avenues for therapeutic intervention in various diseases.