Analytical Data
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Gene name
NEUROD6
- Application
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Alternative Names
Atoh2; NEX1M; Math-2; bHLHa2; Neurogenic differentiation factor 6; Mammalian Atonal Homolog 2; Atonal Homolog 2; Class A basic helix-loop-helix protein 2
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96NK8
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Expression Region
Arg95~Ser272
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Molecular Weight
43kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NEUROD6 is a member of the neurogenic differentiation (NEUROD) family of basic helix-loop-helix transcription factors, which play crucial roles in the development and differentiation of neuronal and endocrine cells. Research into NEUROD6 has gained traction due to its potential implications in neurogenesis and associated neurological disorders. Its expression is predominantly observed in the central nervous system, where it is thought to regulate the maturation of neural progenitor cells and promote the formation of specific neuronal subtypes. Additionally, NEUROD6 has been implicated in various pathological conditions, including neurodegenerative diseases and certain types of cancer, highlighting its importance in both developmental biology and disease mechanisms. The recombinant expression of NEUROD6 protein allows for in-depth studies of its molecular functions and interactions, facilitating the understanding of its role in neuronal differentiation and the broader implications for neuronal plasticity. As such, NEUROD6 offers a promising target for therapeutic strategies aimed at modulating neural development and addressing neurodegenerative diseases, making it a significant focus in current biomedical research.
