Analytical Data
-
基因名
TYROBP
- Application
-
别名
DAP12; KARAP; PLOSL; Killer Activating Receptor Associated Protein; DNAX-Activation Protein 12
-
种属
Human
-
表达系统
E. coli
-
标签
N- His & GST
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O43914
-
表达区间
Leu22~Lys113
-
分子量
42kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TYROBP, also known as TYRO protein tyrosine kinase binding protein, has gained attention in recent years due to its critical role in immune cell signaling and its involvement in various pathological conditions. This adaptor protein interacts with several immunoreceptors and signaling molecules, playing a pivotal role in modulating immune responses, especially within myeloid cells like macrophages and dendritic cells. Research has linked dysregulation of TYROBP to autoimmune diseases, cancer, and neurodegenerative disorders, highlighting its potential as a therapeutic target. In particular, the study of TYROBP recombinant proteins has become a focal point for understanding its structural and functional properties, aiding in the elucidation of its signaling pathways. By producing and characterizing TYROBP recombinant proteins, researchers aim to further investigate its interactions with other proteins and its impact on immune cell activation. This knowledge may provide valuable insights into the development of novel immunotherapies and the design of targeted treatments for TYROBP-related diseases. Overall, TYROBP serves as a crucial component in the immune system, making its study paramount for advancing therapeutic strategies in various health conditions.
