Analytical Data
-
基因名
PSMb6
- Application
-
别名
LMPY; Macropain delta chain; Proteasome subunit Y; Multicatalytic endopeptidase complex delta chain
-
种属
Human
-
表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P28072
-
表达区间
Ala2~Ala239
-
分子量
29kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PSMb6 is a component of the 26S proteasome, a crucial multi-subunit complex responsible for protein degradation in eukaryotic cells. This proteasome plays a vital role in regulating various cellular processes, including the cell cycle, signaling pathways, and the removal of damaged or misfolded proteins. The PSMb6 subunit, specifically, is involved in the assembly and function of the proteasome complex, impacting its efficiency and specificity in substrate recognition and degradation. Recent studies have highlighted the importance of PSMb6 in maintaining cellular homeostasis and its potential implications in cancer biology, where dysregulation of proteasomal activity is often observed. Furthermore, research into the recombinant production of PSMb6 has gained traction, as the availability of high-purity protein is essential for elucidating its structure-function relationships and therapeutic potential. By producing recombinant PSMb6, researchers aim to investigate its role in proteasomal activity, explore its interactions with other proteasome components, and assess its impact on the degradation of specific substrates. Understanding these mechanisms could pave the way for novel therapeutic strategies targeting proteasomal dysfunction in various diseases, including cancer and neurodegenerative disorders.
